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AMA #9: Kratom Risks, Does Infrared Sauna Work & Journaling Benefits
Huberman Lab
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AMA #9: Kratom Risks, Does Infrared Sauna Work & Journaling Benefits
Huberman Lab
Go to Podcast Page
Andrew Huberman
·
13 Clips
·
Jul 28, 2023
AMA #9: Kratom Risks, Does Infrared Sauna Work & Journaling Benefits
Huberman Lab
0 Clips
·
Jul 28, 2023
Top Moments
Now kratom is not known to suppress respiration when taken at low to moderate dosages; but when combined with any other opioids, and certainly when combined with alcohol, it can suppress respiration. And while the data on this are fairly scant, there is some evidence that kratom-induced death is caused by suppression of the respiration
system.
Combining Kratom With Other Opioids & Alcohol Increases Death Risk Via Respiratory Failure
A number of people out there have managed to wean themselves off opioids, such as morphine and hydrocodone through the use of kratom, and that has been used as justification for keeping kratom on the market and keeping it
legal.
Because of Addiction Potential, Andrew Recommends Avoiding Kratom If You Haven't Tried It
When people start taking higher dosages of kratom, it is very clear that it does become addictive and itself is very hard to come off of—so much so that people experience so-called kratom
withdrawal.
Because of Addiction Potential, Andrew Recommends Avoiding Kratom If You Haven't Tried It
The general takeaway from all of that is if you can avoid taking kratom, meaning if you haven't taken it already, don'
t.
Because of Addiction Potential, Andrew Recommends Avoiding Kratom If You Haven't Tried It
Indeed, at low dosages, kratom has a mild stimulant effect. However, at higher dosages, it has what's called an analgesic effect—that is a painkilling effect—and it acts as a sedative, and kratom itself acts as an opioid in the
body.
Kratom Acts as a Stimulant at Low Doses & Analgesic at High Doses
Some of these products will have a higher concentration of one or the other alkaloids within them such that you can't really compare 1g of one brand of kratom to 1g of another brand of kratom because they can have wildly different levels of these different
alkaloids...
Alkaloid Fillers Make Comparing Kratom Dosages Difficult
My advice would be, if you haven't touched kratom, don't touch it at all,
ever.
Forcing Users to Ratchet Up Dosing, Kratom Can Be a Trap
Somewhere between 10 and 40% of people seem to respond to opioids in a particularly potent way. They really like
them.
10-40% of People Respond Potently to Opioids, Increasing Addiction Potential
Kratom and morphine and hydrocodone all have the property of acting like the endogenous opioids but at much higher
potency.
Like Morphine & Hydrocodone, Kratom Preferentially Binds to the Mu Opioid Receptor
While death directly from kratom is fairly rare, it has
happened.
Combining Kratom With Other Opioids & Alcohol Increases Death Risk Via Respiratory Failure
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Huberman Lab Intro
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Clips
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Kratom Acts as a Stimulant at Low Doses & Analgesic at High Doses
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The Opioid Crisis Is Fueled By Overconsumption & Addiction to Opioids
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Because of Addiction Potential, Andrew Recommends Avoiding Kratom If You Haven't Tried It
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Alkaloid Fillers Make Comparing Kratom Dosages Difficult
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10-40% of People Respond Potently to Opioids, Increasing Addiction Potential
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Like Morphine & Hydrocodone, Kratom Preferentially Binds to the Mu Opioid Receptor
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Like Cannabis With Alcohol, Many Claim Kratom Isn't as Bad as Opioids; It's Not Rational
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Combining Kratom With Other Opioids & Alcohol Increases Death Risk Via Respiratory Failure
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Forcing Users to Ratchet Up Dosing, Kratom Can Be a Trap
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Andrew Huberman Outro
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Transcripts
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Clips
Huberman Lab Intro
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Kratom Acts as a Stimulant at Low Doses & Analgesic at High Doses
The Opioid Crisis Is Fueled By Overconsumption & Addiction to Opioids
Because of Addiction Potential, Andrew Recommends Avoiding Kratom If You Haven't Tried It
Alkaloid Fillers Make Comparing Kratom Dosages Difficult
10-40% of People Respond Potently to Opioids, Increasing Addiction Potential
Like Morphine & Hydrocodone, Kratom Preferentially Binds to the Mu Opioid Receptor
Like Cannabis With Alcohol, Many Claim Kratom Isn't as Bad as Opioids; It's Not Rational
Combining Kratom With Other Opioids & Alcohol Increases Death Risk Via Respiratory Failure
Forcing Users to Ratchet Up Dosing, Kratom Can Be a Trap
Andrew Huberman Outro
AD: Huberman Lab Premium
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