AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it

If you look at people with very high C-reactive protein... above 10 milligrams per liter, there hazard ratio for all-cause mortality is 2.71 ... Meaning, at any given year, they have a 171% increase in the risk of death from any cause relative to someone with a low CRP...

There's a very clear relationship between inflammation and excess adiposity that lives outside of the sub-q space ... Sub-q fat is the fat none of us like because we see it in the mirror ... It's the visceral fat, it's the organ fat that we don't see, that's really driving the inflammatory response we want to avoid.

The association between chronic inflammation and the 4 horsemen—so that would be atherosclerotic disease, cancer, and neurodegenerative diseases and metabolic diseases—is incredibly high.

I just hate buzzwords, and inflammation is just such a buzzword that gets thrown around so much with no meaning.

Inflammation is a biological response of the immune system to defend against some sort of stimulus—usually harmful, but not always—and to eliminate the cause of injury.