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How to Optimize Your Hormones for Health & Vitality
Huberman Lab
Go to Podcast Page
How to Optimize Your Hormones for Health & Vitality
Huberman Lab
Go to Podcast Page
Andrew Huberman, Kyle Gillett
·
73 Clips
·
Apr 11, 2022
How to Optimize Your Hormones for Health & Vitality
Huberman Lab
0 Clips
·
Apr 11, 2022
Top Moments
If you calorically restrict mice by 40%, then they can have improved testosterone parameters but only if they're obese to start. And it appears to be that same way in humans as well. So, the easy way to think about it is if you're obese or you have metabolic syndrome, caloric restriction will improve your
testosterone.
Caloric Restriction Increases Testosterone in Men With Metabolic Syndrome
Cannabinoids itself, whether it's THC or CBD, are not going to reduce testosterone by themself. If it's smoked marijuana, then it's very likely to increase your aromatase, which increases your estrogen... So, that is going to decrease
testosterone.
Smoked Marijuana, High Alcohol Intake, & GABA Agonists Decrease Testosterone
The two strongest ones are likely diet and exercise. For hormone health, specifically resistance training is particularly helpful. For diet, caloric restriction can be particularly helpful, especially with the epidemic of metabolic syndrome that is continuing to ongo in this country and in developed countries, in
general.
The 6 Pillars of Hormone Health: Diet, Exercise, Stress, Sleep, Sunlight, & Spirit
There is a study in young, healthy men, and they calorically restrict them, and their testosterone does decrease. So, if you're young & healthy and you don't have metabolic syndrome, then caloric restriction will likely decrease your
testosterone.
Caloric Restriction Increases Testosterone in Men With Metabolic Syndrome
Creatine, like creatine monohydrate, can significantly increase the conversion of testosterone to
DHT.
Turmeric Inhibits Conversion of Testosterone to DHT; Creatine Enhances It
There's a lot of sleep supplements that should not be taken daily, and GABA is one of them. Another one of them is trazodone ... In general, if you're taking a sleep supplement, it should not be taken every
night.
Besides Magnesium & L-Theanine, Sleep Supplements Shouldn't Be Taken Daily
If you are a 80-year-old male and you have an autopsy, there's at least a 50% chance that you had a prostate cancer. If you're 90 or 100-years-old, there's at least a 90% chance. So, for humans with a prostate, it's only a matter of time until you get a prostate
cancer.
Testosterone Supplementation Accelerates Prostate Cancer Growth
Testosterone is not going to cause a prostate cancer. However, normal aging causes prostate cancer, and testosterone will grow your prostate
cancer.
Testosterone Supplementation Accelerates Prostate Cancer Growth
Grass-fed butter has good omega-3 content, as well. So, grass-fed foods... are one of the only sources of healthy trans
fat.
Grass-Fed Foods Are One of the Few Healthy Trans Fat Sources
I've got the question a lot, 'How do you get your doctor to order a better lab workup or to even include your basic hormones?' And there's no magic answer to that. But what really helps is you tell them, 'My energy is not as good as it used to be. My focus is not as good as they used to be. My athletic performance is not as good as it used to
be.'
How to Get Your Doctor to Order Blood Work That Measures Hormone Health
If a man begins TRT, then they develop poor sleep because of sleep apnea. It drastically raises the risk that somebody is going to have sleep
apnea.
TRT Increases Sleep Apnea Risk, Faciliating Poor Sleep
Let's say you have a diet high in plant polyphenols. Many of those inhibit the enzyme that converts testosterone to
DHT.
Turmeric Inhibits Conversion of Testosterone to DHT; Creatine Enhances It
PCOS is polycystic ovarian syndrome. And this is one of those conditions which is under-diagnosed. So, its prevalence is much higher than we think it is. There's been a lot of studies, and some studies say prevalence of 10%; some say 20%. It's not completely clinically penetrant. So, most people don't know they have PCOS until they have infertility or
subfertility.
PCOS Symptoms Include Insulin Resistance, Androgen Excess, & Infertility
The more you're doing your zone 2 cardiovascular exercise, the slightly less important a long duration of caloric restriction
is.
Hormone Optimization: Zone 2 Cardio Reduces the Need for Caloric Restriction
If you have a growth hormone deficiency, a true deficiency, whether you're an adult or a child, then your sleep is likely going to be
affected.
Menopausal Women Experience Poor Sleep Because of Low Progestin Activity
If your offspring are females, then you're slightly more likely to have prostate
cancer.
Elevated CRP & Female Offspring Increase Prostate Cancer Risk
Intros & Ads
Andrew Introduces Dr. Kyle Gillett (Part I)
AD: The Brain-Body Contract
Disclaimer
AD: Thesis
AD: InsideTracker
AD: ROKA
Andrew Introduces Dr. Kyle Gillett (Part II)
Clips
1
Dr. Kyle Gillett's Med School Education Emphasized Preventive Medicine
0
Share
2
How to Get Your Doctor to Order Blood Work That Measures Hormone Health
0
Share
3
Hormone Health Is a Barbed Wire Topic Among the General Public
0
Share
4
The 6 Pillars of Hormone Health: Diet, Exercise, Stress, Sleep, Sunlight, & Spirit
3
Share
5
Take an Individualized Approach When Optimizing Your Diet for Hormone Health
0
Share
6
Dr. Kyle Gillett Recommends Getting Blood Work Every 3-6 Months
0
Share
7
Hormone Optimization: Zone 2 Cardio Reduces the Need for Caloric Restriction
0
Share
8
Caloric Restriction Increases Testosterone in Men With Metabolic Syndrome
3
Share
9
Intermittent Fasting Increases Growth Hormone, Particularly in Older Individuals
1
Share
10
Sauna or Exercise-Stimulated Growth Hormone Pulses Likely Don't Increase Cancer Risk
0
Share
11
Menopausal Women Experience Poor Sleep Because of Low Progestin Activity
0
Share
12
TRT Increases Sleep Apnea Risk, Faciliating Poor Sleep
1
Share
13
Women Have More Total Testosterone Than Estrogen & More DHEA Than Either
0
Share
14
The Androgen Receptor Gene Comes from the Mother's Father, Influencing Baldness Risk
0
Share
15
DHT Is Closely Tied to Heart Health in Men & Women
2
Share
16
Turmeric Inhibits Conversion of Testosterone to DHT; Creatine Enhances It
2
Share
17
Finasteride Is a Potent 5-Alpha Reductase Inhibitor; Side Effects Are Reversible
1
Share
18
Because of DHT Effects, Creatine Monohydrate Can Exacerbate Hair Loss
0
Share
19
Dr. Kyle Gillett Recommends Localized Dustaserine Injections for Treating Hair Loss
0
Share
20
PCOS Symptoms Include Insulin Resistance, Androgen Excess, & Infertility
0
Share
21
Tools for Reducing PCOS Risk: Metformin, Inositol, & DIM
0
Share
22
Oral Contraceptives Alter Female Assessment of Male Attractiveness
0
Share
23
Certain Oral Contraceptives Increase Risk of Blood Clots
0
Share
24
Oral Contraceptives Likely Don't Accelerate the Transition to Infertility
0
Share
25
Smoked Marijuana, High Alcohol Intake, & GABA Agonists Decrease Testosterone
1
Share
26
Besides Magnesium & L-Theanine, Sleep Supplements Shouldn't Be Taken Daily
1
Share
27
Testosterone Supplementation Accelerates Prostate Cancer Growth
0
Share
28
Diets High in Prebiotic Fiber Reduce Colitis Risk, Improving Prostate Health
0
Share
29
Elevated CRP & Female Offspring Increase Prostate Cancer Risk
0
Share
30
Often Taken to Treat Erectile Dysfunction, Low-Dose Tadalafil (2-5 mg) Improves Prostate Health
1
Share
31
The Optimal TRT Dose: 100-120mg, Divided Into 2-3 Injections
1
Share
32
Dr. Gillett Recommends Most People Avoid Aromatase Inhibitors
0
Share
33
Dr. Gillett Recommends Calcium D-Glucarate & DIM for Lowering Estrogen
0
Share
34
HCG, Found in Pregnant Women's Urine, Upregulates Aromatase & Increases Testosterone
0
Share
35
Grass-Fed Foods Are One of the Few Healthy Trans Fat Sources
0
Share
36
Ecdysterone & Turkesterone Support Healthy Testosterone & Estrogen Ratios
1
Share
37
Tongkat Ali Reduces Estrogen By Decreasing Aromatase, Elevating Testosterone
0
Share
38
Women With Hyperestrogenism Should Consider Supplementing With Tongkat Ali
0
Share
39
Dr. Gillett Recommends Cycling Tongkat Ali: 11 Months On, 1 Month Off
0
Share
40
Fadogia Agrestis Increases Testosterone By Stimulating Luteinizing Hormone Release
2
Share
41
3-6 mg of Boron Once or Twice Daily Lowers SHBG, Increasing Testosterone
3
Share
42
Human Chorionic Gonadotropin (HCG) Improves Thyroid Health & Fertility
0
Share
43
HCG's Effect on Nerve Cells in the Genitals Can Makes Sexual Activity More Pleasurable
0
Share
44
Wanna Fake a Positive Pregnancy Test? Inject HCG
0
Share
45
Dopamine Agonists, Like L-Tyrosine, Decrease Activity of Prolactin-Producing Cells
0
Share
46
Tools for Decreasing Prolactin: Ceasing Casein Intake, P5P/Vitamin B6, & Vitamin E
0
Share
47
For Enhanced Fertility, Dr. Gillett Recommends 10 g/Day of Capsulized L-Carnitine
0
Share
48
600 mg/Day of Allicin (Garlic) Reduces TMAO Levels
2
Share
49
Injectable L-Carnitine Is 100% Bioavailable; Dr. Gillett Recommends >200 mg/Day for Fertility
0
Share
50
Dr. Gillett Doubts Hormone Blood Tests Will Ever Be Covered By Insurance
0
Share
51
Regular Time Apart Facilitates Optimal Hormone Health Among Romantic Partners
0
Share
52
Prolactin Helps With the Nesting Instinct; It Spikes Post-Breastfeeding
0
Share
53
Cold Exposure to Warm Testes Increases Testosterone, Particularly in Men With a Varicocele
2
Share
54
Avoid Using the Sauna If You're Infertile or Have a Low Sperm Count
1
Share
55
In Women, Cold Exposure Increases Activity of Beta-Adrenergic Receptors
0
Share
56
Dr. Kyle Gillett's Favorite Peptide Is the Original Peptide: Insulin
0
Share
57
Because It Spikes Growth Hormone, Tesamorelin Increases Cancer Risk
1
Share
58
Recommended Dosing Frequency for BPC-157, a VEGF-Increasing Peptide That Accelerates Healing
2
Share
59
Andrew Recommends Avoiding Non-Prescription Forms of BPC-157
2
Share
60
Melanotan Is FDA Approved for Treatment of Low Libido & Lipodystrophy
1
Share
61
Why Spirituality Is Dr. Kyle Gillett's 6th Pillar of Hormone Health
0
Share
62
Unless It Impairs Sleep, Caffeine Has Negligible Effects on Hormone Health
0
Share
63
Andrew & Kyle Outro
0
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64
Andrew Huberman Outro (Part I)
0
Share
65
Thorne
0
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66
Andrew Huberman Outro (Part II)
0
Share
Transcripts
View Full Episode Transcript
Clips
Andrew Introduces Dr. Kyle Gillett (Part I)
AD: The Brain-Body Contract
Disclaimer
AD: Thesis
AD: InsideTracker
AD: ROKA
Andrew Introduces Dr. Kyle Gillett (Part II)
Dr. Kyle Gillett's Med School Education Emphasized Preventive Medicine
How to Get Your Doctor to Order Blood Work That Measures Hormone Health
Hormone Health Is a Barbed Wire Topic Among the General Public
The 6 Pillars of Hormone Health: Diet, Exercise, Stress, Sleep, Sunlight, & Spirit
Take an Individualized Approach When Optimizing Your Diet for Hormone Health
Dr. Kyle Gillett Recommends Getting Blood Work Every 3-6 Months
Hormone Optimization: Zone 2 Cardio Reduces the Need for Caloric Restriction
Caloric Restriction Increases Testosterone in Men With Metabolic Syndrome
Intermittent Fasting Increases Growth Hormone, Particularly in Older Individuals
Sauna or Exercise-Stimulated Growth Hormone Pulses Likely Don't Increase Cancer Risk
Menopausal Women Experience Poor Sleep Because of Low Progestin Activity
TRT Increases Sleep Apnea Risk, Faciliating Poor Sleep
Women Have More Total Testosterone Than Estrogen & More DHEA Than Either
The Androgen Receptor Gene Comes from the Mother's Father, Influencing Baldness Risk
DHT Is Closely Tied to Heart Health in Men & Women
Turmeric Inhibits Conversion of Testosterone to DHT; Creatine Enhances It
Finasteride Is a Potent 5-Alpha Reductase Inhibitor; Side Effects Are Reversible
Because of DHT Effects, Creatine Monohydrate Can Exacerbate Hair Loss
Dr. Kyle Gillett Recommends Localized Dustaserine Injections for Treating Hair Loss
PCOS Symptoms Include Insulin Resistance, Androgen Excess, & Infertility
Tools for Reducing PCOS Risk: Metformin, Inositol, & DIM
Oral Contraceptives Alter Female Assessment of Male Attractiveness
Certain Oral Contraceptives Increase Risk of Blood Clots
Oral Contraceptives Likely Don't Accelerate the Transition to Infertility
Smoked Marijuana, High Alcohol Intake, & GABA Agonists Decrease Testosterone
Besides Magnesium & L-Theanine, Sleep Supplements Shouldn't Be Taken Daily
Testosterone Supplementation Accelerates Prostate Cancer Growth
Diets High in Prebiotic Fiber Reduce Colitis Risk, Improving Prostate Health
Elevated CRP & Female Offspring Increase Prostate Cancer Risk
Often Taken to Treat Erectile Dysfunction, Low-Dose Tadalafil (2-5 mg) Improves Prostate Health
The Optimal TRT Dose: 100-120mg, Divided Into 2-3 Injections
Dr. Gillett Recommends Most People Avoid Aromatase Inhibitors
Dr. Gillett Recommends Calcium D-Glucarate & DIM for Lowering Estrogen
HCG, Found in Pregnant Women's Urine, Upregulates Aromatase & Increases Testosterone
Grass-Fed Foods Are One of the Few Healthy Trans Fat Sources
Ecdysterone & Turkesterone Support Healthy Testosterone & Estrogen Ratios
Tongkat Ali Reduces Estrogen By Decreasing Aromatase, Elevating Testosterone
Women With Hyperestrogenism Should Consider Supplementing With Tongkat Ali
Dr. Gillett Recommends Cycling Tongkat Ali: 11 Months On, 1 Month Off
Fadogia Agrestis Increases Testosterone By Stimulating Luteinizing Hormone Release
3-6 mg of Boron Once or Twice Daily Lowers SHBG, Increasing Testosterone
Human Chorionic Gonadotropin (HCG) Improves Thyroid Health & Fertility
HCG's Effect on Nerve Cells in the Genitals Can Makes Sexual Activity More Pleasurable
Wanna Fake a Positive Pregnancy Test? Inject HCG
Dopamine Agonists, Like L-Tyrosine, Decrease Activity of Prolactin-Producing Cells
Tools for Decreasing Prolactin: Ceasing Casein Intake, P5P/Vitamin B6, & Vitamin E
For Enhanced Fertility, Dr. Gillett Recommends 10 g/Day of Capsulized L-Carnitine
600 mg/Day of Allicin (Garlic) Reduces TMAO Levels
Injectable L-Carnitine Is 100% Bioavailable; Dr. Gillett Recommends >200 mg/Day for Fertility
Dr. Gillett Doubts Hormone Blood Tests Will Ever Be Covered By Insurance
Regular Time Apart Facilitates Optimal Hormone Health Among Romantic Partners
Prolactin Helps With the Nesting Instinct; It Spikes Post-Breastfeeding
Cold Exposure to Warm Testes Increases Testosterone, Particularly in Men With a Varicocele
Avoid Using the Sauna If You're Infertile or Have a Low Sperm Count
In Women, Cold Exposure Increases Activity of Beta-Adrenergic Receptors
Dr. Kyle Gillett's Favorite Peptide Is the Original Peptide: Insulin
Because It Spikes Growth Hormone, Tesamorelin Increases Cancer Risk
Recommended Dosing Frequency for BPC-157, a VEGF-Increasing Peptide That Accelerates Healing
Andrew Recommends Avoiding Non-Prescription Forms of BPC-157
Melanotan Is FDA Approved for Treatment of Low Libido & Lipodystrophy
Why Spirituality Is Dr. Kyle Gillett's 6th Pillar of Hormone Health
Unless It Impairs Sleep, Caffeine Has Negligible Effects on Hormone Health
Andrew & Kyle Outro
Andrew Huberman Outro (Part I)
Thorne
Andrew Huberman Outro (Part II)
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