Estrogen, in lots of ways, could be summarized by: If you had a choice in the matter between having a lot of estrogen in your bloodstream or not, go for having a lot of estrogen. It enhances cognition... It stimulates neurogenesis in the hippocampus. It increases glucose and oxygen delivery. It protects you from dementia. It decreases inflammatory oxidative damage to blood vessels, which is why it's good for protecting from cardiovascular disease...