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The observation that is unequivocal is hyperinsulinemia is associated with worse outcomes in ASCVD. The most obvious example of that is type 2 diabetes, which is just a very extreme manifestation of hyperinsulinemia.
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Peter Attia

Hyperinsulinemia & Type 2 Diabetes Increase ASCVD Risk Via Insulin's Action on APOC3

AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease

The Peter Attia Drive

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Hyperinsulinemia & Type 2 Diabetes Increase ASCVD Risk Via Insulin's Action on APOC3

Hyperinsulinemia & Type 2 Diabetes Increase ASCVD Risk Via Insulin's Action on APOC3

AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease - Peter Attia
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Hyperinsulinemia & Type 2 Diabetes Increase ASCVD Risk Via Insulin's Action on APOC3
AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease - Peter Attia
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AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease - Peter Attia
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